Caffeine addiction is in the genes
Coffee drinkers finally have an excuse for their addiction – it is written in their genes, say the U.S. scientists.
American scientists are searching for links as why some people are addicted to caffeine on examined genetic variations in more than 40 thousand individuals. They found two sets of DNA associated with consuming tea, coffee, chocolate, soft drinks and other sources of caffeine. These two sequences contain two genes that are associated with the way the body processes caffeine. First, CYP1A2, and previously was known as a gene that participates in the breakdown of caffeine. Second, AHR, helps to regulate the former one.
Scientists have found that people who carry the so-called. variation of high consumption of any of these two genes drink more coffee than those with a variant of low consumption. That is, the former on average consume 40 milligrams of caffeine per day more than others.
Author of the study, Neil Caporaso said that this is in fact an incredible story. He also added that people do not expect that, but genetics plays a major role in behavior, including, as we see, and how much caffeine we drink.
Caporaso says that we’ve known for decades that CYP1A2 is responsible for caffeine addiction, but now we are using the new technology first demonstrated that the gene is responsible for inherited differences in the amount of coffee we drink among people.
Caffeine is the most popular stimulant in the world, 90 percent of the population uses it in one form or another.